10 April 2013

Hesperidin Derivatives























Hesperidin Derivatives, belongs to class of vitamin p compounds analogues, having the functions fo reducing abnormity general characteristics and brittleness of thin blood vessel. It can be used to prevent the and cure of hybertensive and the cure of arteriosclerotic. The hemostasia curative effect is better than rutin and hesperidin.
Diosmin is effective in Venous ulcers which  affect approximately 1% of the world's population.
It has Anti-inflammatory activity in rat colitis induced by TNBS.
Prospective randomized controlled trial of a diosmin found  to reduce bleeding after haemorrhoidectomy.
diosmin is  of its use in chronic venous insufficiency, venous ulcers and haemorrhoids.
 leg ulcer healing helps on microcirculation. diosmin has the  properties  pertaining to inflammation, cellular basis of inflammation, edema .it acts in venous hypertension, inflammation and valve remodeling.
It is used for Blood Brain Barrier Compromise with Endothelial Inflammation which may Lead to Autoimmune Loss of Myelin during Multiple Sclerosis. It is supposed to increase vascular tension, and stimulate the lympahtic system.

Details :
Diosmin  is a beige or yellowish crystal powder, it is practically insoluble  in waterand ethanol and  soluble in sodium hydroxide,dmso and  pyridine.
DIOSMIN               : MINM  90% to 104%
IMPURITIES           : NMT 10%
MOISTURE BY KF :   NMT 6%
ASH CONTENT     :  NMT 0.4%
IODINE                  : NMT 0.1%


 METHYL HESPERIDIN
Product: Methyl Hesperidin
Synonyms: Hesperetin-7-rhamnoglucoside
 CAS: 11013-97-1
Molecular formula : C29H36O15
Molecular Weight: 624.59
PLANT SOURCE: peels  of Citrus aurantium L.
PURITY : 94%HPLC
SPECIFICATIONS :
Methyl Hesperidin is a yellow colored powder consisting of  mixture of methylated derivatives of hesperidine which is soluble in water , and ethtanol having a particular odour and bitter taste..
USE:
It belongs to water soluble derivative of commonly called VITAMIN P.
It is used where water insolubility is hindering the use of hesperidine. Hence METHYL HESPERIDINE is having all good effects of hesperidine while having soluble in water in contrast to hesperidine which is water insoluble.
Used For bleedings of nose ,retina ,gingival,gastrointestinal and haemorroids.
Used for formulations of eye liners.
It is also used as a colorant to give yellow color to beverages and at the same time giving the property of an antioxidant
Supports and protects the integrity of the vascular system with particular acitivity in the capillaries and veins. It has been shown to help strengthen capillaries by increasing capillary resistance and decreasing capillary permeability.
Methyl hesperidin is used as dietary supplement, natural healthcare supplement, plant extract, herb extract

Flavonoids Extract 90:10 with Diosmin
PRODUCT
This product is a misture of flavonoids which is containing 90%diosmin and 10% hesperidine,used to treat venous insufficiency.
It belongs to class of vitamin p compounds analogues, having the functions fo reducing abnormity general characteristics and brittleness of thin blood vessel. It can be used to prevent the and cure of hybertensive and the cure of arteriosclerotic. The hemostasia curative effect is better than rutin and hesperidin.
Diosmin is effective in Venous ulcers which  affect approximately 1% of the world's population.
It has Anti-inflammatory activity in rat colitis induced by TNBS.
Prospective randomized controlled trial of a diosmin found  to reduce bleeding after haemorrhoidectomy.
diosmin is  of its use in chronic venous insufficiency, venous ulcers and haemorrhoids.
 leg ulcer healing helps on microcirculation.
diosmin gas the  properties  pertaining to inflammation.
cellular basis of inflammation, edema .it acts in venous hypertension, inflammation and valve remodeling.
It is used for Blood Brain Barrier Compromise with Endothelial Inflammation which may Lead to Autoimmune Loss of Myelin during Multiple Sclerosis.
It is supposed to increase vascular tension, and stimulate the lympahtic system.
SPECIFICATIONS;
Flavonoids mixture  is a beige or yellowish crystal powder, it can hardly dissolve in water, easily dissolve in sodium hydroxide,dmso and  pyridine. It is practically insoluble in water and ethanol.
DIOSMIN               : MINM  90%
HESPERIDINE        :  MINM 10%
MOISTURE BY KF :   NMT 6%
ASH CONTENT     :  NMT 0.4%